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Signs of heart disease in cats

Trouble breathing: breathing rate may be faster, breaths may appear heavier, deeper, or more exaggerated. Some cats with trouble breathing may breathe at a normal rate, but each breath appears to be a deep sigh.
Restlessness (accompanied by change in breathing) – inability to sleep or rest comfortably
Collapse or fainting
Exercise intolerance: In a cat this can be transient heavier breathing after exertion, such as playing or jumping up on furniture, or stopping to lie down after taking a few steps
Cough is rarely a sign of heart disease in cats (it is more commonly due to asthma or other respiratory diseases), however some cats can cough with heart disease
Sudden paralysis or inability to use hind limbs or a forelimb
Behavior change: Although this is not specific for heart disease (it can be a sign of any other illness in a cat), when cats do not feel well they may hide or sleep in unusual places, not greet you at the normal times, or be less affectionate. Since cats are very good at hiding how they feel, it is important to have a cat evaluated when they are not acting like themselves.

Some of these signs can also occur with other disease processes. A cardiac evaluation can determine if these signs are heart-related or not.
Cats can also have heart disease without having any obvious signs at all.
Trouble breathing is an emergency; cats with trouble breathing should go to their nearest emergency hospital.